Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:37 AM
Ignite Modification Date:
2025-12-25 @ 12:37 AM
NCT ID:
NCT01477567
Eligibility Criteria:
Inclusion Criteria:
* Are a healthy male or a female who cannot become pregnant
* Have a body mass index (BMI) of 18.5 to 32.0 kilograms per meter squared (kg/m\^2) at screening
* Have blood pressure, pulse rate, as well as blood and urine laboratory test results acceptable for the study
* Have veins suitable for easy blood collection
* Are reliable and willing to be available for the whole study and be willing to follow study procedures
* Have given consent to participate in this study
Exclusion Criteria:
* Are currently participating in or were in another new drug or device or in any medical research study in the last 30 days
* Currently have or used to have allergies or other health problems or laboratory test results that in the opinion of the doctor, could make it unsafe for the participant to participate, or interfere with understanding the results of this study
* Have received live vaccine(s) within 1 month of screening, or intend to during the study
* Have received treatment with biologic agents (such as monoclonal antibodies) within 3 months or 5 half-lives (whichever is longer) prior to dosing
* Have a weakened immune system
* Have previously completed or withdrawn from this study
* Have illnesses or conditions that may increase risk when taking the study medication or interfere with the interpretation of data in this study
* Have electrocardiogram (ECG) readings that are not suitable for the study
* Are using or intend to use over-the-counter medications or prescription medications within 7 and 14 days (respectively) from the start of the first study dosing until end of the study
* Have a history of drug or alcohol abuse
* Are infected with hepatitis B
* Are infected with human immunodeficiency virus (HIV)
* Have donated 450 milliliters (mL) or more of blood in the last 3 months or made any blood donation within the last month
* Have a regular alcohol intake greater than 21 units per week (males) and 14 units per week (females) or are unwilling to abstain from alcohol 24 hours before dosing until the completion of each inpatient study period
* Smoke more than 10 cigarettes per day or are unable or unwilling to refrain from smoking while at the clinic
* Are unwilling or unable to follow dietary requirements/restrictions for the study and only consume only the meals provided during inpatient stays at the clinical research unit
* Are deemed unsuitable to participate by the study doctor for any other reasons
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
21 Years
Maximum Age:
65 Years
Study:
NCT01477567
Study Brief:
Protocol Section:
NCT01477567