Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:37 AM
Ignite Modification Date:
2025-12-25 @ 12:37 AM
NCT ID:
NCT07262567
Eligibility Criteria:
Inclusion Criteria:
* Voluntarily participate in the study and sign the informed consent form.
* Male or female aged 18-80 years (inclusive) at the time of signing the informed consent form.
* Pathologically confirmed pancreatic cancer (derived from pancreatic ductal epithelium) at metastatic stage.
* Have received at least one prior standard systemic therapy.
* Participants must have at least one measurable lesion (per RECIST 1.1 criteria).
* Expected survival time ≥ 12 weeks as judged by the investigator.
* Have adequate organ function
Exclusion Criteria:
* Other malignant tumors that progressed or required treatment within 3 years prior to randomization.
* With active central nervous system (CNS) metastasis.
* Previous receipt of therapy targeted for KRAS G12D or pan-RAS/KRAS.
* Received radiotherapy within 4 weeks prior to randomization or other local anti-tumor therapy within 4 weeks prior to randomization.
* Received other anti-tumor therapy within 28 days or 5 half-lives (whichever is shorter) prior to randomization.
* With clinically significant severe cardiovascular diseases.
* Stroke or other severe cerebrovascular diseases within 6 months prior to randomization.
* Complicated with major acute or chronic infectious diseases.
* Have severe mental or psychological diseases, or a history of drug abuse or severe alcoholism.
* Pregnant or lactating females.
* Other conditions deemed inappropriate for participation in the study by the investigator.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
80 Years
Study:
NCT07262567
Study Brief:
Protocol Section:
NCT07262567