Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:36 AM
Ignite Modification Date:
2025-12-25 @ 12:36 AM
NCT ID:
NCT06253767
Eligibility Criteria:
Inclusion Criteria:
* Patients with endodontic involvement in three-rooted (upper molars) or two-rooted (upper premolars) teeth.
* Age between 20 and 75 years.
* Both genders.
Exclusion Criteria:
* Pregnancy or lactation.
* Patients with oncological, renal, or Type I or Type II diabetes.
* Drug users; alcohol or tobacco users.
* Immunocompromised patients or those using immunosuppressive medication.
* Use of alendronate, bisphosphonates, or any systemic medication that interferes with bone metabolism.
* Presence of associated periodontal disease.
* Frequent exacerbations.
* Radiolucency images with PAI stages 3, 4, or 5 (Orstavik et al., 1986).
* Any other anatomical variation that renders single-session endodontic treatment unfeasible.
* Teeth with previous endodontic treatment.
* Patients with asymptomatic non-microbial apical periodontitis with any type of bruxism (clenching) or using a bite splint.
* Teeth with more than ⅔ coronal involvement, making proper use of rubber dam isolation impossible.
* Use of antibiotics in the last three months.
* History of severe allergy to chlorine or its derivatives.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
20 Years
Maximum Age:
75 Years
Study:
NCT06253767
Study Brief:
Protocol Section:
NCT06253767