Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:36 AM
Ignite Modification Date:
2025-12-25 @ 12:36 AM
NCT ID:
NCT07080567
Eligibility Criteria:
Inclusion Criteria:
* Informed consent as documented by signature
* ≥18 years at time of signing of informed consent
* Acute ischemic stroke.
* Stroke onset \< 7 days from randomization.
* Contralateral, unilateral, incomplete upper limb paresis, incl. :
* FMA-UE \< 63/66
* Residual voluntary finger extension (VFE) of \> 10 degrees
Exclusion Criteria:
* Pregnancy/lactation or positive pregnancy test in women of childbearing age
* Pre-stroke handicap (mRS \> 2)
* Diseases affecting motor function (e.g., Parkinson's Disease, Amyotrophic Lateral Sclerosis (ALS))
* Participation in another study with investigational medicinal product within 30 days preceding and during the present study
* Enrolment of the investigator, his/her family members, employees, or other dependent persons
* Known hypersensitivity to Maraviroc, Mannitol, peanuts, or soy
* History of significant liver disease, hepatitis, elevated liver function tests (\> 1.5 upper limit of normal)
* History of significant renal disease or End Stage Renal Disease/dialysis, acute renal injury, Creatinine Clearance (CrCl \< 30ml/min/1.73m2)
* Patients with cardiovascular comorbidities and risk for orthostatic hypotension
* HIV infection
* Concomitant use of strong CYP3A4 inhibitors or inducers
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07080567
Study Brief:
Protocol Section:
NCT07080567