Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:36 AM
Ignite Modification Date:
2025-12-25 @ 12:36 AM
NCT ID:
NCT00173667
Eligibility Criteria:
Inclusion Criteria:
* Male or non-pregnant female patients aged 18-70 years.
* Patients had hypertension with sitting systolic blood pressure 140-180 mmHg, or diastolic blood pressure 90-110 mmHg.
* Patients must give written informed consent to participate in this study.
Exclusion Criteria:
* Women who are pregnant or nursing.
* Patients have the evidence of secondary or malignant hypertension, history of severe heart disease, cerebrovascular accident within one year, or myocardial infarction within six months.
* Patients receiving more than one anti-hypertensive agents or one antihypertensive agent with maximal recommended dosage before entrance into the trial.
* Patients with uncontrolled diabetes mellitus.
* Patients had known hypersensitivity or contraindication to nifedipine, other calcium channel blockers or other beta-adrenergic antagonists.
* Patients have the evidences of hepatic dysfunction (AST, ALT\> 3 times upper limit of normal value), renal dysfunction (serum creatinine concentration\>1.5 mg/dl), pulmonary dysfunction, mental disorders or other concurrent severe disease.
* As to the study of flow-mediated dilatation and oxidative stress, patients with diabetes mellitus, dyslipidemia, body mass index \>27, and smokers will be excluded.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT00173667
Study Brief:
Protocol Section:
NCT00173667