Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:34 AM
Ignite Modification Date:
2025-12-25 @ 12:34 AM
NCT ID:
NCT07158567
Eligibility Criteria:
Inclusion Criteria:
* 1 mo. stability in pain management strategies.
* 22+ years of age.
* Can read and speak English.
* Able to participate in strengthening, stretching, range of motion exercise via yoga as determined by study physician.
* Chronic Low Back Pain (CLBP): pain in the low back that persists for \>6 months and is of moderate to severe intensity with a score of \>5 on specific items on the BPI demonstrating disability of at least 20% on the Oswestry Disability Index (ODI).
Exclusion Criteria:
* Contraindications to iTBS/TMS (e.g. epilepsy, psychotic spectrum disorders \[i.e. bipolar, schizophrenia\], history of anoxic brain injury).
* Moderate to severe heart disease.
* Contraindications to MRI (e.g., claustrophobia, implanted ferromagnetic device such as pacemaker or cardiac defibrillator).
* Pain believed to be associated with cardiac or ischemic conditions.
* Epilepsy, active seizure disorder, personal history of a seizure or individuals with a family history of epilepsy or seizure in a first degree relative.
* Current prescription of psychostimulants (e.g., amphetamines), anticholinergics, tricyclic antidepressants, and antipsychotics or other medications that may increase their risk of having seizures.
* Intracranial lesion.
* History of ischemic or hemorrhagic stroke.
* History of moderate to severe TBI.
* History of or current psychosis not due to an external cause (e.g., due to illicit drug use).
* Other neurological conditions (e.g., neurodegenerative disorders).
* Active suicidal ideation with Columbia Suicide Severity Rating Scale(CSSRS) 3 .
* Are pregnant or nursing.
* Within 12 weeks of a major surgery/operation.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
22 Years
Study:
NCT07158567
Study Brief:
Protocol Section:
NCT07158567