Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:33 AM
Ignite Modification Date:
2025-12-25 @ 12:33 AM
NCT ID:
NCT04908267
Eligibility Criteria:
Inclusion Criteria (if we will predict the molecular status and overall survival):
* the patient was over 18 years old
* the lesion was located in the supratentorial space;
* a histopathologic diagnosis of HGGs according to the WHO CNS4/5;
* all subjects were the first diagnosed cases without any invasive or non-invasive treatment;
* access to the complete preoperative MR imaging examinations, at least including four conventional sequences.
Inclusion Criteria (if we will differentiate recurrence from distant intracranial recurrence):
* the patient was over 18 years old;
* the lesion was located in the supratentorial space;
* a histopathologic diagnosis of HGGs according to the WHO CNS4/5;
* underwent concurrent chemoradiotherapy with temozolomide after surgical resection or biopsy;
* underwent preoperative and postoperative MRI, at least including four conventional sequences;
* had newly appeared or enlarging, measurable, contrast-enhancing mass which raises clinical suspicion of tumor recurrence and distant intracranial recurrence;
* adequate follow-up examinations to determine treatment response on clinic-radiological consensus or pathologic confirmation.
Exclusion Criteria:
* patient with other brain tumors or other grade gliomas at the same time;
* patient with severe basic diseases at the same time;
* patient with a survival time of less than 30 days, which can be caused by severe surgical trauma stress;
* poor image quality and heavy artifact affect the subsequent image processing.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04908267
Study Brief:
Protocol Section:
NCT04908267