Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:32 AM
Ignite Modification Date:
2025-12-25 @ 12:32 AM
NCT ID:
NCT06258967
Eligibility Criteria:
Inclusion Criteria:
* Age ≥ 65 years and age \< 90 years.
* ASA (American Society of Anesthesiologists) physical status classification 1-3.
* Scheduled for elective general anesthesia surgery.
Exclusion Criteria:
* Participants already enrolled in other studies or those already assigned in this study .
* BMI (Body Mass Index) ≤ 18 or ≥ 30 kg/m2.
* Preoperative assessment indicating a challenging airway or a risk of aspiration, requiring a slow induction for intubation.
* Presence of severe liver or kidney disease (GFR ≤ 30 ml/min/1.73m2 or requiring renal replacement therapy; Child-Pugh class C for liver function).
* Patients with severe uncontrolled hypertension (preoperative SBP ≥ 180 mmHg or DBP ≥ 110 mmHg).
* Individuals with arrhythmias and severe valvular diseases, including high-degree atrioventricular block (Mobitz type II or third-degree block); symptomatic bradycardia; symptomatic ventricular arrhythmias; prolonged Q-T interval; supraventricular arrhythmias combined with an uncontrolled ventricular rate \> 100 bpm (at rest); new-onset ventricular tachycardia; uncontrolled atrial fibrillation (ventricular rate ≥ 110 bpm); atrial flutter; severe aortic valve stenosis (mean pressure gradient \> 40 mmHg; valve area \< 1 cm2; symptomatic); severe mitral valve stenosis (progressive breathlessness during exertion; exertional syncope; heart failure).
* Patients diagnosed with schizophrenia, epilepsy, Parkinson's disease, severe cognitive impairment, intellectual disability, hearing impairment.
* Individuals with a history of alcoholism or long-term use of sedatives and analgesics.
* Previous allergic reactions to medications used in this study.
* Individuals already under vasoconstrictor treatment before anesthesia induction.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
65 Years
Maximum Age:
90 Years
Study:
NCT06258967
Study Brief:
Protocol Section:
NCT06258967