Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:31 AM
Ignite Modification Date:
2025-12-25 @ 12:31 AM
NCT ID:
NCT00483067
Eligibility Criteria:
Inclusion Criteria:
1. Patient must have diagnosis of idiopathic HES, defined as (1) no recent history of allergic reaction or parasitic infection; (2) sustained (\> 6 months) hypereosinophilia (1,500/mm\^3); and (3) signs or symptoms of organ involvement.
2. Age less than 76 years old.
3. Patient is not pregnant.
4. Zubrod performance status \< 3.
5. Life expectancy is not severely limited by concomitant illness.
6. Serum creatinine \< 2 mg/dL.
7. Serum bilirubin \< 2 times upper limit of normal (2 mg/dL).
8. Alanine aminotransferase (SGPT) \< 2 times upper limit of normal (112 IU/L).
9. Participant has completed the informed consent process, understands the investigational nature of the study, agrees to participate, and has signed the informed consent.
Exclusion Criteria:
1. Evidence of chronic active hepatitis or cirrhosis, and \> 1 month from prior episode of hepatitis.
2. Presence of an active infection.
3. HIV positive.
4. Has eosinophilic leukemia (defined by presence of clonal cytogenetic abnormalities).
5. Recent history of parasite infection.
6. Recent history of allergic reaction.
Healthy Volunteers:
False
Sex:
ALL
Maximum Age:
76 Years
Study:
NCT00483067
Study Brief:
Protocol Section:
NCT00483067