Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:28 AM
Ignite Modification Date:
2025-12-25 @ 12:28 AM
NCT ID:
NCT06464367
Eligibility Criteria:
Inclusion criteria:
* Age 21 to 70 (inclusive)
* Migraine disease per ICHD-3 criteria (for migraine participants) OR Healthy control patient
Exclusion criterion
* Unstable medical condition or serious nervous system pathology
* Pregnant, breastfeeding, lack of adequate birth control
* Psychotic or manic disorder
* Substance abuse in the prior 3 months
* Use of classic psychedelics (e.g., psilocybin, LSD, mescaline) in the past 6 months
* Use of cannabis or other THC products in the prior 2 weeks
* Urine toxicology positive to drugs of abuse
* The use of triptans (e.g., sumatriptan) or ditans (e.g., lasmiditan) more than twice weekly on average
* Use of serotonergic preventive therapies (i.e., taken chronically; amitriptyline, fluoxetine, imipramine, cyproheptadine) in the past 6 weeks
* Use of preventive or transitional treatments that produce spikes and waning of symptom relief (e.g., botulinum toxin, calcitonin gene-related peptide system targeting antibodies, peripheral nerve or ganglion blocks, chiropractic manipulation)
* History of a bleeding disorder or are currently taking anticoagulants (e.g., warfarin, enoxaparin, dabigatran, apixaban).
* Use of non-steroidal anti-inflammatory drugs (NSAIDs; e.g., ibuprofen, naproxen) in the 7 days before PET scan and 7 days after PET scan.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
21 Years
Maximum Age:
70 Years
Study:
NCT06464367
Study Brief:
Protocol Section:
NCT06464367