Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:19 AM
Ignite Modification Date:
2025-12-25 @ 12:19 AM
NCT ID:
NCT07092358
Eligibility Criteria:
Inclusion Criteria:
* Presence of progressive ataxia as a primary or persistent clinical feature;
* Sufficient evidence to exclude acquired causes of ataxia (e.g., chronic intoxication, immune-mediated inflammation, acquired vitamin deficiency, acute injury, stroke, infection, or space-occupying disorders);
* For sporadic late-onset cases (≥30 years), disease duration must exceed 3 years, with no prominent progressive autonomic dysfunction or other features indicative of multiple system atrophy-cerebellar type (MSA-C);
* Ability and willingness of the participant or legal guardian to provide informed consent and complete the entire study process.
Exclusion Criteria:
* Patients whose causative genes identified through genetic testing and analysis do not fall within the defined spectrum of hereditary ataxias, based on consensus classifications from the MDS Task Force on Genetic Movement Disorders and the SRCA Working Group, along with current research advancements;
* Presence of concurrent cerebrovascular disease, brain tumors, or severe systemic illness;
* Refusal to sign informed consent or provide biological samples by the participant or legal representative;
* Inability or unwillingness to participate in follow-up assessments.
Healthy Volunteers:
False
Sex:
ALL
Study:
NCT07092358
Study Brief:
Protocol Section:
NCT07092358