Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:16 AM
Ignite Modification Date:
2025-12-25 @ 12:16 AM
NCT ID:
NCT02279758
Eligibility Criteria:
Inclusion Criteria:
* Metastatic well-differentiated neuroendocrine tumor grade 1 or 2 with histological confirmation;
* Performance status according to Eastern Cooperative Oncology Group (ECOG) 0 to 2;
* Able to take pills;
* Age ≥ 16 years;
* Ability to Provide Written Informed Consent;
* Adequate organ function;
Exclusion Criteria:
* Patient with out of control severe hormonal syndrome;
* Diabetic patients under metformin treatment, or those who have received treatment with metformin within 3 months;
* Patient with hypersensitivity to biguanides, kidney or liver failure, or other conditions that predispose to lactic acidosis;
* History of severe clinical or psychiatric illness, that would prevent participation in the study by clinical judgment;
* Patients who participate in other protocol with experimental drugs;
* Patients under any kind of active infection;
* Patients who have received chemotherapy within 3 weeks;
* Patients pregnant or lactating;
* Diabetic patients who require higher dose of metformin 850mg x 2 daily;
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
16 Years
Study:
NCT02279758
Study Brief:
Protocol Section:
NCT02279758