Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:14 AM
Ignite Modification Date:
2025-12-25 @ 12:14 AM
NCT ID:
NCT01582958
Eligibility Criteria:
Inclusion Criteria:
* postbronchodilator FEV1/FVC \<0.7 and FEV1 \<80% predicted \[FEV1 =volume that has been exhaled at the end of the first second of forced expiration\] and FVC volume of air that can be forcibly blown out after full inspiration\]
* history of smoking \>20 pack-years
* stable condition at inclusion with no infection or exacerbation for at least two months
* optimal medical therapy for at least eight weeks with no change
Exclusion Criteria:
* history of active pulmonary disease such as asthma
* positive bronchodilator test
* treatment with N-acetylcysteine
* previous diagnosis of hypertension or current anti-hypertensive treatment
* known unstable or moderate to severe heart disease (arrhythmia, ischemic heart disease, or cardiomyopathy)
* previous diagnosis of chronic illness such as diabetes, renal failure, hypercholesterolemia, hepatic cirrhosis, cancer, rheumatoid arthritis or any other systemic inflammatory disease
* neuromuscular or disabling cognitive problems
* engagement in any exercise-training program during the past three months
* substance abuse in the preceding six months
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
49 Years
Maximum Age:
80 Years
Study:
NCT01582958
Study Brief:
Protocol Section:
NCT01582958