Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:14 AM
Ignite Modification Date:
2025-12-25 @ 12:14 AM
NCT ID:
NCT06772558
Eligibility Criteria:
Inclusion Criteria:
* Age \> 70 years
* American Society of Anesthesiologists (ASA) physical status classification I-III
* Scheduled to undergo elective surgery requiring general anesthesia with desflurane
* Able and willing to provide voluntary written informed consent
* Able to understand the study procedures and complete follow-up assessments
Exclusion Criteria:
* Pre-existing diagnosis of dementia or any other neurodegenerative disease that could affect cognitive function
* Preoperative Montreal Cognitive Assessment (MoCA) score \< 20
* History of severe psychiatric disorders, including psychosis, severe depression, or bipolar disorder
* Unstable angina, uncontrolled hypertension, or a history of myocardial infarction within the past 6 months
* Severe chronic obstructive pulmonary disease (COPD) with significant respiratory compromise, or other significant respiratory disease
* Severe hepatic or renal impairment, defined as Child-Pugh class C for liver disease, or glomerular filtration rate (GFR) \< 30 mL/min/1.73 m2 for kidney disease
* History of stroke, transient ischemic attack (TIA), or other significant neurological disorders
* History of alcohol or drug abuse
* Patients with visual, auditory, or language impairments that would interfere with cognitive testing.
* Known allergy or contraindication to any of the study drugs
* Other conditions at the discretion of the investigator that could interfere with the conduct of the study or the interpretation of the results
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
70 Years
Study:
NCT06772558
Study Brief:
Protocol Section:
NCT06772558