Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:14 AM
Ignite Modification Date:
2025-12-25 @ 12:14 AM
NCT ID:
NCT07135258
Eligibility Criteria:
Inclusion Criteria:
1. Age of 18 years or above
2. History of persistent or permanent AF (valvular or non-valvular). Persistent AF refers to sustained AF beyond 7 days. Permanent AF is defined as uninterrupted AF with duration of \>1 year with nil plan of restoration of sinus rhythm
3. A 12-leads electrocardiogram (ECG) at baseline with documented heart rate \>/= 80 bpm
4. Acceptance of rate control as the main management strategy, taking into consideration of recent clinical evidence, patient conditions and preference, as decided by clinical assessment prior to randomization
5. Provision of informed consent
Exclusion Criteria:
1. Patients aged under 18 years
2. Patients who were pregnant
3. Those who were not in persistent or permanent AF
4. Baseline heart rate \<80bpm on ECG
5. Pre-existing high grade atrioventricular block, or medically unfit for heart rate reduction as assessed by attending clinician prior to randomization
6. Hemodynamic instability, including those who require electrical cardioversion
7. Known hypersensitivity to ivabradine or medication components
8. Patients who do not accept rate control as mainstay of treatment strategy
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07135258
Study Brief:
Protocol Section:
NCT07135258