Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:12 AM
Ignite Modification Date:
2025-12-25 @ 12:12 AM
NCT ID:
NCT06308458
Eligibility Criteria:
Inclusion Criteria:
* Age range 65-75 years old of both genders
* Oriented elder subjects assessed for cognitive impairment with score greater than 30 on Mini- Mental Scale.
* Healthy elders with normal pulmonary function test values according to reference values.
Exclusion Criteria:
* Using any medications affect muscular strength.
* Active hemoptysis, untreated pneumothorax, recent esophageal surgeries.
* Acute or chronic pulmonary diseases, or decompensated heart failure.
* Acute upper respiratory stenosis 'true vocal fold mass, vocal fold paralysis in adducted position, sub-glottic stenosis' or recent oral, facial or skull trauma or surgeries, also acute sinusitis, epistaxis, hemodynamic instability, tympanic membrane rupture, or acute middle ear pathology 'otitis or labyrinthitis'.
* Active smokers.
* Subjects with previous neurological disorders affecting respiratory muscles or any muscular dystrophies.
* Subjects with previous cervical or thoracic surgeries.
* Presence of hemodynamic instability 'heart rate more than 150beat per minute, or systolic blood pressure more than 140 mmHg, or diastolic blood pressure more than 90 mmHg'
* Presence of severe cognitive impairments affects their understanding of any steps of study protocol.
* Uncooperative individuals during chest ultrasound measurement that require performance of deep inspiration and full expiration.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
65 Years
Maximum Age:
75 Years
Study:
NCT06308458
Study Brief:
Protocol Section:
NCT06308458