Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:12 AM
Ignite Modification Date:
2025-12-25 @ 12:12 AM
NCT ID:
NCT06281158
Eligibility Criteria:
Inclusion Criteria:
* Males, aged between 18 to 65 years, inclusive
* Body mass index between 18.0 and 32.0 kg/m2
* In good health
* When engaging in sex with a woman of child bearing potential, both the male participant and his female partner must use highly effective contraception
* History of a minimum of 1 bowel movement per day
Exclusion Criteria:
* History or clinical manifestation of any clinically significant metabolic, allergic, dermatological, hepatic, renal, hematological, pulmonary, cardiovascular, gastrointestinal, neurological, respiratory, endocrine, or psychiatric disorder
* Have a history of malignancy, except fully resected basal cell carcinoma
* History of significant hypersensitivity, intolerance, or allergy to any drug compound, food, or other substance
* History of stomach or intestinal surgery or resection that would potentially alter absorption and/or excretion of orally administered drugs
* Have previously completed or withdrawn from this study or any other study investigating DNL343 and have previously received DNL343
Healthy Volunteers:
True
Sex:
MALE
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT06281158
Study Brief:
Protocol Section:
NCT06281158