Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:11 AM
Ignite Modification Date:
2025-12-25 @ 12:11 AM
NCT ID:
NCT00988858
Eligibility Criteria:
Inclusion Criteria:
* Must agree to have a tumor biopsy at screening
* Must have a diagnosis of advanced or metastatic non-squamous non-small cell lung cancer that has progressed after certain prior treatment
* Must be available for the duration of the study and willing to follow the study procedures
* If participant is a woman that is capable of having children, must have a negative pregnancy test within 7 days of taking first dose of study drug
* Must have discontinued radiation therapy at least 4 weeks before entering this study
Exclusion Criteria:
* Must not have taken an unapproved drug as treatment for any indication within the last 28 days before starting study treatment.
* Must not be pregnant or lactating, are considering becoming pregnant, or are considering fathering a child. Males and females with reproductive potential must agree to use medically approved contraceptive precautions during the trial until the participant's physician considers it safe to become pregnant or father a child.
* Must not have known positive test in human immunodeficiency virus (HIV), hepatitis B surface antigen (HBSAg), or hepatitis C antibodies (HCAb).
* Must not have previously participated in a study involving LY2603618
* Must not have previously taken pemetrexed for cancer
* Must not have a known allergy to LY2603618 or pemetrexed
* Must not currently have an infection that may affect participant's ability to tolerate the therapy
* Must not have a serious medical condition or disorder that would make it unsafe for you to participate in the study such as uncontrolled diabetes or chest pain due to heart disease
* If taking certain medications called non-steroidal anti-inflammatory drugs (NSAIDS), such as ibuprofen, must be able to stop taking these medications according to certain guidelines
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00988858
Study Brief:
Protocol Section:
NCT00988858