Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:09 AM
Ignite Modification Date:
2025-12-25 @ 12:09 AM
NCT ID:
NCT04392258
Eligibility Criteria:
Inclusion Criteria:
* Admission after cardiopulmonary resuscitation
* Minimum age of 18 years
* Results of TSH and peripheral thyroid hormone concentrations already available or possibility to reorder these investigations in a post-hoc manner if consent has been obtained (i. e. time interval after venipuncture within the storage period of the central laboratory)
* Inclusion after own consent of the patient after reawakening, via custodian or independent consultant.
Exclusion Criteria:
* Missing data on thyroid homeostasis in the first blood specimen (obtained before 3 hours after admission)
* Traumatic brain injury
* Persistent hints for thyroid dysfunction, not explained by non-thyroidal illness syndrome (NTIS) / euthyroid sick syndrome (ESS) / thyroid allostasis in critical illness, tumors, uremia and starvation (TACITUS) in consecutive investigations over several days after resuscitation
* Functionally relevant thyroid or pituitary disorder, as documented in international classification of diseases (ICD) codes.
* Exposure to radiocontrast agents less than 3 months ago
* Therapy with amiodarone (currently or during the previous 3 years)
* Pregnancy
* Known thyroid disease
* Consent not obtained within the routine storage period of the central laboratory
* Post-hoc-exclusion if evidence for true dysfunction the the pituitary or the thyroid became available during the study period.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04392258
Study Brief:
Protocol Section:
NCT04392258