Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:07 AM
Ignite Modification Date:
2025-12-25 @ 12:07 AM
NCT ID:
NCT02305758
Eligibility Criteria:
Inclusion Criteria:
* Histologically or cytologically confirmed metastatic adenocarcinoma of the colon or rectum
* At least 1 unresectable lesion on a CT (Computerized Tomography) scan that is measurable as defined by Response Evaluation Criteria in Solid Tumors (RECIST), Version 1.1
* ECOG (Eastern Cooperative Oncology Group) performance score of 0 or 1
* Adequate hematologic, renal and hepatic function
Exclusion Criteria:
* Prior anti-cancer treatment for metastatic colorectal cancer
* Prior exposure to PARP (poly ADP-ribose polymerase) inhibitors
* The last course of adjuvant or neoadjuvant chemotherapy must have ended \> 12 months prior to Cycle 1 Day -2
* Any clinically significant and uncontrolled major medical condition
* Participant is pregnant or lactating
* Any medical condition, which in the opinion of the study Investigator, places the participant at an unacceptably high risk for toxicities
* For those receiving bevacizumab, standard medical exclusionary conditions apply
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
99 Years
Study:
NCT02305758
Study Brief:
Protocol Section:
NCT02305758