Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:04 AM
Ignite Modification Date:
2025-12-25 @ 12:04 AM
NCT ID:
NCT03527758
Eligibility Criteria:
Inclusion Criteria:
* Aged 18 years or older;
* Planned for elective non-cardiac non-day surgery with an expected duration of more than 2 hours;
* Planned to receive general anesthesia;
* Planned to receive an arterial line during surgery;
* Aim for MAP of 65 mmHg during surgery;
* Being able to give written informed consent prior to surgery.
Exclusion Criteria:
Age less than 18 years;
* Aim for MAP other than 65 mmHg at discretion treating physician;
* Significant hypotension before surgery defined as a MAP \<65;
* Right- or left sided cardiac failure \[e.g. left ventricular ejection fraction (LVEF)\<35%\];
* Known cardiac shunts (significant);
* Known aortic stenosis (severe);
* Severe cardiac arrhythmias including atrial fibrillation;
* Chronic kidney disease (as chronic kidney disease may affect the interpretation and prognostic significance of changes in urinary biomarkers);
* Liver surgery;
* Vascular surgery with clamping of the aorta;
* Diabetes.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
21 Years
Maximum Age:
80 Years
Study:
NCT03527758
Study Brief:
Protocol Section:
NCT03527758