Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:03 AM
Ignite Modification Date:
2025-12-25 @ 12:03 AM
NCT ID:
NCT06767358
Eligibility Criteria:
Inclusion Criteria:
* Adult patients (≥ 18 years) admitted to the ICU
* Receiving invasive mechanical ventilation and expected to remain mechanically ventilated beyond the calendar day after randomization
* Mechanically ventilated for fewer than 3 days
* Receiving any non-ketamine continuous sedative infusion
Exclusion Criteria:
* Admitted with a primary diagnosis of intracranial hemorrhage, traumatic brain injury, or stroke
* Admitted with uncontrolled hypertension (SBP/DBP \> 180/100mmHg)
* Status asthmaticus
* Admitted to the ICU with partial thickness burns \> 10% total body surface area or any full thickness burns
* Schizophrenia
* End-stage Liver Failure (Child-Pugh C)
* Requiring an equivalent of norepinephrine at a dose ≥1mcg/kg/min
* Undergoing palliation or comfort care
* On neuromuscular blocking agent
* Pre-existing tracheostomy
* Hypersensitivity to Ketamine
* Liver transplantation in the last month
* Pregnant or breast-feeding
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT06767358
Study Brief:
Protocol Section:
NCT06767358