Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:03 AM
Ignite Modification Date:
2025-12-25 @ 12:03 AM
NCT ID:
NCT02470858
Eligibility Criteria:
Inclusion Criteria:
* Age equal to or greater than 18 years, with chronic genotype 1b HCV infection;
* HCV RNA level \> 10,000 and \< 10,000,000 IU/ml at Screening;
* Rapid response to triple DAAs therapy with less than 500 IU/ml plasma HCV RNA level at Day 2;
* No evidence of cirrhosis. Cirrhosis defined as any 1 of the following, within 6 months of study entry:
1. Liver biopsy showing cirrhosis;
2. Fibroscan showing cirrhosis or results\>12.5 kPa ;
3. FibroTest® score \>0.75 and an aspartate aminotransferase (AST): platelet ratio index (APRI) \>2 during screening.
Exclusion Criteria:
* Pregnant or nursing female or male with pregnant female partner;
* HIV or chronic hepatitis B virus (HBV) infection;
* Hematologic or biochemical parameters at Screening outside the protocol-specified requirements;
* Active or recent history (≤ 1 year) of drug or alcohol abuse;
* Hepatocellular carcinoma or other malignancy (with exception of certain resolved skin cancers);
* History or current evidence of any condition, therapy, laboratory abnormality or other circumstance that might confound the results of the study, or interfere with the subject's participation for the full duration of the study, such that it is not in the best interest of the subject to participate.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02470858
Study Brief:
Protocol Section:
NCT02470858