Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 1:56 PM
Ignite Modification Date:
2025-12-24 @ 1:56 PM
NCT ID:
NCT03553095
Eligibility Criteria:
Inclusion Criteria:
* At least 18 years old
* Must be a patient of the UAB Dental School
* Able to read and understand informed consent document
* Good general health as evidenced by medical history
* Minimum of 18 teeth, excluding third molars
* Having moderate to severe periodontal disease according to AAP definition (teeth ≥5 mm PD and ≥3 mm CAL)
* Having \>30 percent bleeding sites upon probing
* Patients taking depression medication with chronic periodontitis
* Patients without depression with chronic periodontitis
* Patients who have not had a dental cleaning in the past 3 months prior to procedure
* Patients scheduled for surgical procedures (i.e. gum surgery, tooth extraction, or dental implants)
Exclusion Criteria:
* Non-English speaking
* Less than 18 years old
* Smokers/tobacco users (\>10 cigarettes/day)
* Any dental condition that requires immediate treatment, such as emergency care
* Chronic use (≥3 times/week) of anti-inflammatory medications (e.g., non-steroidal anti-inflammatory drugs, steroids). Low-dose aspirin (less than 325 mg daily)
* Immunocompromised subjects
* Any medical history or any concomitant medication that might affect the assessment of the study treatment or periodontal tissues, such as uncontrolled diabetes, nifedipine, phenytoin (Dilantin), subjects with arthritis and morbidly obese (BMI ≥ 40)
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
99 Years
Study:
NCT03553095
Study Brief:
Protocol Section:
NCT03553095