Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:01 AM
Ignite Modification Date:
2025-12-25 @ 12:01 AM
NCT ID:
NCT00715858
Eligibility Criteria:
Inclusion Criteria:
* Giving informed consent to lumbar puncture
* Participation in the DARAD clinical trial which requires the following:
* diagnosis of probable Alzheimer's disease
* SMMSE 14-26 inclusive
* community-dwelling
* age 50 or greater
* caregiver to monitor study medication and report on ADLs, behaviour, etc.
* adequate English literacy to complete neuropsychological testing
* generally stable level of health
Exclusion Criteria:
* Contraindication to lumbar puncture
* DARAD exclusion criteria as follows:
* dementia due to other neurodegenerative diseases
* cognitive impairment due to head trauma, etc.
* stroke or significant cerebrovascular disease
* clinically significant cardiac disease such as recent MI, uncontrolled hypertension
* taking other anti-dementia treatments or investigational drugs
* allergy to doxycycline or rifampin
* significant psychiatric conditions like depression
* cancer
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
50 Years
Study:
NCT00715858
Study Brief:
Protocol Section:
NCT00715858