Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:01 AM
Ignite Modification Date:
2025-12-25 @ 12:01 AM
NCT ID:
NCT00805558
Eligibility Criteria:
Inclusion Criteria:
* 18 years of age and up
* clinical and radiographic signs of severe (CAL 5 mm or more) chronic periodontitis.
* at least 20 natural teeth in situ
* pocket probing depths (PPDs) of ≥ 5 mm at a minimum of eight tooth sites
* willingness to participate and to be available at all times required for participation
* over 30% of the teeth present must have a PPDs)≥ 4 mm and insertion loss ≥ 5 mm evaluated by an experienced periodontist
* informed consent signed by the patient
Exclusion Criteria:
* if they (or parents or siblings) show confirmed or assumed allergies or hyper-sensitive skin reactions against moxifloxacin, ciprofloxacin (or other quinolones as listed in the "summary of product characteristics, Version Juli 2005"), metronidazole (or other 5-nitroimidazoles and ingredients of Flagyl® 400mg as listed in the "summary of product characteristics, Version Juli 2007"), systemic diseases or conditions as listed in the above mentioned "summary of product characteristics"
* subjects who have undergone antibiotic therapy three months before the start of the study under interrogation
* have Down's syndrome
* known AIDS/HIV
* regularly take systemic medication affecting the periodontal conditions, e.g. phenytoin, nifedipine, and/or steroid drugs
* professional periodontal therapy during 6 months prior to baseline
* require antibiotic treatment for dental appointments
* are pregnant or breastfeeding
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00805558
Study Brief:
Protocol Section:
NCT00805558