Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:59 PM
Ignite Modification Date:
2025-12-24 @ 11:59 PM
NCT ID:
NCT01148758
Eligibility Criteria:
Inclusion Criteria:
* adult patients, \>/=19 years of age
* metastatic or unresectable colorectal or ovarian cancer refractory to, or unsuitable for standard therapy
* presence of tumor lesions suitable for DCE-MRI evaluation
* WHO performance status 0-1
* adequate bone marrow, liver and renal function
Exclusion Criteria:
* patient unsuitable for MRI scanning (e.g. metal implants, pacemaker, claustrophobia, hypersensitivity to DCE-MRI contrast material)
* brain metastases
* clinically significant ascites
* active bleeding, bleeding diathesis, oral anti-vitamin K medication (other than low dose coumarin) or history of coagulation disorders
* radiation therapy within 3 weeks, or anti-neoplastic therapy \<30 days prior to first dose of study drug
* chronic therapy with systemic steroids or another immunosuppressive agent \<2 weeks prior to first dose of study drug
* treated with bevacizumab in last regimen of systemic therapy
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
19 Years
Study:
NCT01148758
Study Brief:
Protocol Section:
NCT01148758