Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:58 PM
Ignite Modification Date:
2025-12-24 @ 11:58 PM
NCT ID:
NCT03989258
Eligibility Criteria:
Inclusion Criteria:
Cohort 1:
* Available NGS (WGS or WES) data for detection of breast cancer moderate to high genetic risk variants in BRCA1, BRCA2, TP53, STK11, PTEN, CDH1, ATM, PALB2, CHEK2, NBN, NF1 genes;
* Available genetic (WGS, genotyping) data for PRS calculation, participants in age 40-74 will be further selected;
Cohort 2:
* Available genotyping data;
* No available NGS data for BRCA1, BRCA2, TP53, STK11, PTEN, CDH1, ATM, PALB2, CHEK2, NBN, NF1 genes;
* Participants in the age group 40-74 with available genetic data for PRS calculation;
Cohort StMG:
• Female participants in Estonian Biobank in the age group 50-69 participating at least once in the current Estonian population-based screening program during 2016-2020.
Exclusion Criteria:
Cohort 1: breast cancer in the medical history; Cohort 2: breast cancer in the medical history. Cohort StMG: none.
Healthy Volunteers:
False
Sex:
FEMALE
Minimum Age:
25 Years
Study:
NCT03989258
Study Brief:
Protocol Section:
NCT03989258