Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:56 PM
Ignite Modification Date:
2025-12-24 @ 11:56 PM
NCT ID:
NCT04283851
Eligibility Criteria:
Inclusion Criteria:
* patients after elective coronary artery bypass grafting
* hypovolemia indicated for volumotherapy by the attending physician based on clinical and laboratory signs (ScvO2 under 65 % with serum lactate above 2 mmol/l, increase of vasopressoric support with CVP under 5 mmHg)
* intubated and ventilated patients
* sedation without spontaneous breathing activity
* no pulmonary pathology on X-ray after surgery
* normal systolic and diastolic function of both ventricles (left ventricular ejection fraction above 50 %, TAPSE of the right ventricle above 20 mm, FAC of the right ventricle above 30 %)
* informed consent signed before surgery
Exclusion Criteria:
* aggresive artificial ventilation (PEEP above 10 cmH2O, Pmax above 30 cm H2O)
* ARDS, pneumothorax, fluidothorax
* hemodynamically significant valvular disease
* atrial fibrillation or other arrhythmia with irregular heartbeat
* intraabdominal hypertension with pressures above 15 mmHg
* open thorax
* bad echogenicity
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04283851
Study Brief:
Protocol Section:
NCT04283851