Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:54 PM
Ignite Modification Date:
2025-12-24 @ 11:54 PM
NCT ID:
NCT00675051
Eligibility Criteria:
Inclusion Criteria:
* Patient's + 18 years with suspected pre-capillary pulmonary hypertension
* Prescribed Endothelial - 1 receptor blocker
Exclusion Criteria:
* Currently taking endothelium-active vasodilator therapy.
* Hemoglobin and / or hematocrit level blood the lower normal limit.
* Left ventricle dysfunction (LVEF \<50%)
* LV end-diastolic pressure \> 15 mmHg)
* Recent history (\<3 months) of pulmonary embolism
* Liver failure or abnormal liver function tests; aortic or mitral regurgitation or stenosis
* Current medication with endothelin-1 receptor antagonist, prostacyclin analogues or type 5 phosphodiesterase inhibitors.
* Subjects with conditions known to be associated with an increase in circulating endothelial microparticle numers, such as chronic renal failure (Creatinine Clearance \< 50 ml/min/m2) acute coronary syndromes and uncontrolled system hypertension.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
100 Years
Study:
NCT00675051
Study Brief:
Protocol Section:
NCT00675051