Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:54 PM
Ignite Modification Date:
2025-12-24 @ 11:54 PM
NCT ID:
NCT01111851
Eligibility Criteria:
Inclusion Criteria:
* Generally healthy
* Female participants must be of non-childbearing potential
* Non-smoker or has not used nicotine or nicotine-containing products for at least 6 months
Exclusion Criteria:
* History of a clinically significant psychiatric disorder over the last 5 to 10 years
* History of stroke, chronic seizures, or major neurological disorder
* History of clinically significant endocrine, gastrointestinal, cardiovascular, hematological, hepatic, immunological, renal, respiratory, or genitourinary abnormalities or diseases
* History of neoplastic disease
* Excessive consumption of alcohol (3 drinks/day) or caffeinated beverages (6 servings/day)
* Major surgery, donated or lost 1 unit of blood within 4 weeks
* Participated in another investigational study within 4 weeks
* History of significant drug allergy or any clinically significant adverse
experiences related to EMEND™, dexamethasone, or ondansetron
* History of significant multiple and/or severe allergies
* History of anaphylactic reaction or significant intolerability to prescription or non-prescription drugs or food
* Current drug/alcohol abuse, or history of such within 2 years
* Participation in a PET study or other study involving administration of a radioactive substance or ionizing radiation within the prior 12 months
* Extensive radiological examination within the prior 12 months
* Magnetizable metal prostheses or devices (Magnetic Resonance Imaging (MRI) hazard)
* History of claustrophobia
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
55 Years
Study:
NCT01111851
Study Brief:
Protocol Section:
NCT01111851