Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:54 PM
Ignite Modification Date:
2025-12-24 @ 11:54 PM
NCT ID:
NCT05252351
Eligibility Criteria:
In order to be eligible to participate in this study, a subject must meet the following criteria:
* Aged ≥ 18 years
* Capable of understanding and signing informed consent.
Inclusion criteria for the CAS study are patients diagnosed with a valvular congenital aortic stenosis. Two groups of patients will be included:
* Patients with a prior aortic valve replacement (AVR)
* Patients without a prior AVR and with an aortic jet velocity ≥ 2.5 m/s.
Exclusion Criteria:
* Patients with severe aortic regurgitation
* Presence of any of the following contra-indications for MRI
* Contra-indication to gadolinium based contrast media (eGFR \<30 ml/min or contrast allergy)
* Other contra-indications such as presence of pacemaker/implantable cardioverter defibrillator, severe claustrophobia or pregnancy
* Patients known with or previously treated because of aortic coarctation.
* Patients known with genetic syndromes or connective tissue disorders
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT05252351
Study Brief:
Protocol Section:
NCT05252351