Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:52 PM
Ignite Modification Date:
2025-12-24 @ 11:52 PM
NCT ID:
NCT00184951
Eligibility Criteria:
Inclusion Criteria:
* use of lopinavir 400mg/ritonavir 100mg bid \> 3months
* HIV-1 RNA \<400cop/mL
* fasting total cholesterol \> 6.2mmol/L
Exclusion Criteria:
* history of sensitivity/idiosyncrasy to the drug or compounds used
* history or current condition that might interfere with absorption,distribution metabolism or excretion
* pregnant or breast-feeding
* serum transaminase levels \>3 times upper limit of normal, creatinine clearance \<60ml/min
* fasting plasma triglycerides level \>8.0 mmol/L
* history of statin-related rhabdomyolysis or inheritable muscle diseases in family history
* clinical symptoms of myopathy or abnormal CK level
* change in antiretroviral medication within the 3 months immediately preceding first dose of rosuvastatin
* use of any statin or fibrate within 6 weeks immediately preceding first dose of rosuvastatin
* concomitant use of medications that interfere with rosuvastatin or lopinavir pharmacokinetics
* active hepatobiliary or hepatic disease
* hypothyroidism
* alcohol abuse
* japanese or chinese patients
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT00184951
Study Brief:
Protocol Section:
NCT00184951