Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:52 PM
Ignite Modification Date:
2025-12-24 @ 11:52 PM
NCT ID:
NCT00949351
Eligibility Criteria:
Inclusion Criteria:
* Type2 diabetes patients
* Age \<30yrs-70yrs\>
* Overt proteinuria (Urinary protein creatinine ratio \> 200mg/g 2 times or more during past 6 Mo)
* Scr \< 2.5 mg/dL
* HbA1C \< 7.5
* Systolic blood pressure \> 160 mmHg without antihypertensive drugs or \> 140 with antihypertensive drug
* No history of previous cardiovascular event (Stroke, Myocardial infarction, unstable angina, hospitalization, surgical correction PVD or PVD with claudication)
* No hospitalization within 1 yr except for elective surgery
Exclusion Criteria:
* Physical examination found or suspected serious co-morbid (AF, carotid bruit, structural heart disease, cirrhosis and decompensate liver disease)
* Non adherence to protocol
* Intolerable to ACEI or ARB during run-in
* Abnormal liver function test at the run-in period
* Rapid declining renal function (SCr increase \> 40%) during run-in
* Hyperkalemia (serum K \> 5.5 mEq/L at randomization)
* Malignancy detected o
* SBP lower than 110 mmHg (at randomization)
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
30 Years
Maximum Age:
70 Years
Study:
NCT00949351
Study Brief:
Protocol Section:
NCT00949351