Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:51 PM
Ignite Modification Date:
2025-12-24 @ 11:51 PM
NCT ID:
NCT02506751
Eligibility Criteria:
Inclusion Criteria:
* Must meet 2010 McDonald criteria for clinically definite MS
* Must be euthyroid
* Expanded Disability Status Scale (EDSS) 3.0-7.5
* Patients may be on MS immunomodulating therapies or immunosuppressant therapies during the study
Exclusion Criteria:
* Known thyroid disease (past or current)
* Currently on thyroid replacement therapy
* Steroid use within a month of screening
* History of coronary artery disease, atrial fibrillation, or other clinically significant cardiac disease
* History of adrenal insufficiency
* Ongoing renal and/or liver disease
* Ongoing severe depression and/or anxiety
* Use of carbamazepine, phenytoin, phenobarbital, warfarin, antacids, cholestyramine, colestipol, sucralfate, and rifampin
* Known contraindication to using beta-blocker medications
* History of alcohol or substance abuse in the past 6 months
* Pregnant or nursing
* If the investigator feels that participation in this study is not in the best interest of the subject
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
58 Years
Study:
NCT02506751
Study Brief:
Protocol Section:
NCT02506751