Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:51 PM
Ignite Modification Date:
2025-12-24 @ 11:51 PM
NCT ID:
NCT04074551
Eligibility Criteria:
Inclusion Criteria:
* Age ≥ 19
* Patients who understood the contents and purpose of this trial and signed informed consent form
* Patients with essential hypertension and dyslipidemia
Exclusion Criteria:
* Patients with differences between arms greater than 20 mmHg for mean sitSBP or 10 mmHg for mean sitDBP
* Patients with mean sitSBP ≥ 180 mmHg or mean sitDBP ≥ 110 mmHg
* Concomitant administration of cyclosporine
* Tolerance or Hypersensitivity Angiotensin II receptor blocker or HMG-CoA reductase inhibitor, Calcium channel blocker(dihydropyridine) or Multi-drug allergy
* Hereditary angioedema or medical history of angioedema in the treatment of ACE inhibitors or angiotensin II receptor blockers
* Fibromyalgia, myopathy, rhabdomyolysis or acute myopathy or medical history of adverse effect to statin
* CPK normal range \> 2 times
* Secondary hypertension and suspected secondary hypertension
* Orthostatic hypotension with symptoms
* Uncontrolled primary hypothyroidism(TSH normal range ≥ 1.5 times)
* Severe hepatopathy or active hepatopathy (AST or ALT normal range ≥ 3 times)
* Active gout or hyperuricemia(uric acid ≥ 9mg/dL)
* IDDM or uncontrolled type 2 diabetes mellitus (HbA1c \> 9%)
* Ventricular arrhythmia
* Medical history
* Severe heart disease(heart failure of NYHA class III-IV)
* Severe cerebrovascular disease within 6 months (cerebral infarction, cerebral hemorrhage), hypertensive encephalopathy, transient cerebral ischemic attack(TIA)
* Hypertrophic obstructive cardiomyopathy, severe obstructive coronary artery disease, aortic stenosis, hemodynamically significant stenosis in aortic valve or mitral valve
* Ischemic heart disease(myocardial infarction, angina) within 6months
* Angioplasty or coronary artery bypass graft(CABG) surgery within 6months
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
19 Years
Study:
NCT04074551
Study Brief:
Protocol Section:
NCT04074551