Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:47 PM
Ignite Modification Date:
2025-12-24 @ 11:47 PM
NCT ID:
NCT00264251
Eligibility Criteria:
Inclusion Criteria:
* HIV-infected or uninfected.
* Body mass index (BMI) at least 25.
* Excess visceral adipose tissue. Excess VAT will be determined in HIV+ and HIV- groups of men by a waist hip ratio \> 0.95 and a waist circumference \>88.2 cm, and in women by a waist:hip \>0.9 and waist circumference \>75.3 cm.
* Insulin resistance (fasting serum insulin level \>16 μU/ml).
Exclusion Criteria:
* Unable to tolerate magnetic resonance imaging (MRI)
* Clinical evidence of active liver disease or a significantly abnormal liver function test (ALT \>2.5x the upper limit of normal).
* Severe hyperlipidemia (fasting plasma triglycerides \>500 mg/dL or fasting total cholesterol \>300mg/dL)
* Current coronary artery disease including angina
* Peripheral vascular disease
* Uncontrolled hypertension
* Participation in a regular exercise program
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
20 Years
Maximum Age:
60 Years
Study:
NCT00264251
Study Brief:
Protocol Section:
NCT00264251