Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:47 PM
Ignite Modification Date:
2025-12-24 @ 11:47 PM
NCT ID:
NCT02764151
Eligibility Criteria:
Inclusion Criteria:
* Diagnosis of WHO Grade IV glioblastoma or WHO Grade III anaplastic gliomas
* For patients with Grade IV GBM, recurrent disease at the time of the first or second recurrence or progression. For patients with Grade III anaplastic gliomas, recurrent disease at the time of at least a first recurrence but no more than a fourth recurrence or progression
* Karnofsky performance score greater than or equal to 70%
* Adequate bone marrow, kidney and liver function
Exclusion Criteria:
* History of CNS bleeding within 6 months of registration
* Previous anti-angiogenics or anti-vascular endothelial growth factor within 12 months of registration
* Requires treatment with high dose systemic corticosteroids defined as \>2 mg/day
* Radiation therapy within 12 weeks of registration
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02764151
Study Brief:
Protocol Section:
NCT02764151