Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 11:13 PM
Ignite Modification Date:
2025-12-26 @ 11:13 PM
NCT ID:
NCT06293612
Eligibility Criteria:
Inclusion Criteria:
* Newly diagnosed non-mucinous LARC (T3\~T4, or any T with N1\~2, M0) without previous treatment;
* No concomitant malignancies or systemic disease;
* Complete standard neoadjuvant chemoradiotherapy (NCRT) and radical surgery in our institute;
* Underwent rectal MRI and colonoscopy within 2 weeks before NCRT.
Exclusion Criteria:
* Fail to meet any of the inclusion criteria;
* Inadequate MR image quality for analysis, or lack of biopsy tissue for TSR assessment;
* Incomplete clinical data or withdraw before last visit.
A total of 578 eligible LARC cases were initially reviewed, 276 of which were excluded according to the exclusion criteria. Finally, 302 patients were enrolled in this study and randomized into a training cohort (n ＝ 211) and validation cohort (n ＝ 91).
Healthy Volunteers:
False
Sex:
ALL
Study:
NCT06293612
Study Brief:
Protocol Section:
NCT06293612