Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 11:12 PM
Ignite Modification Date:
2025-12-26 @ 11:12 PM
NCT ID:
NCT06920212
Eligibility Criteria:
Inclusion Criteria:
* The patients (aged 50-85 years) exhibited cognitive decline persisting for over six months;
* Primarily characterized by recent memory impairment and accompanied by reduced daily living abilities;
* MMSE scores ranging from 3 to 26;
* MRI findings revealed atrophy in the medial temporal lobe, hippocampus, and cerebral cortex, along with widened sulci and fissures.
Exclusion Criteria:
* Patients were excluded if they had severe visual, hearing, or language impairments;
* Tumors;
* hepatic/renal dysfunction.
* with conditions mimicking AD symptoms-such as normal pressure hydrocephalus, vascular dementia (VD or VaD);
* Parkinson's disease dementia (PDD)-were also excluded;
* patients who had participated in clinical drug trials within the past 30 days or consumed folate and vitamin B12 at doses exceeding twice the recommended intake were ineligible.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
50 Years
Maximum Age:
85 Years
Study:
NCT06920212
Study Brief:
Protocol Section:
NCT06920212