Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 1:48 PM
Ignite Modification Date:
2025-12-24 @ 1:48 PM
NCT ID:
NCT03406195
Eligibility Criteria:
Inclusion Criteria:
* Healthy controls in the age group 60-80 years old
* No other Diagnostic and Statistical Manual of Mental Disorders (DSM) 5 axis 1 diagnoses
* Willing to provide informed consent
* Structural magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) data available
Exclusion Criteria:
* Subjects are unable or unwilling to give informed consent
* Presence of any organic brain illness
* Presence or history of stroke, traumatic brain injury or head injury with loss of consciousness, transient ischemic attack (TIA), any diagnosed neurological disorder including but not limited to multiple sclerosis, Huntington's disease, Parkinson's disease, dementia or major neurocognitive disorder.
* Presence of cranial metal implants, structural brain lesion including but not limited to cerebral aneurysms.
* Presence of devices that may be affected by repetitive transcranial magnetic stimulation (rTMS) (pacemaker, medication pump, cochlear implant, implanted brain stimulator)
* Current or recent (within the past 6 months) substance abuse or dependence, excluding nicotine and caffeine.
* Current serious medical illness
* History of seizure except those therapeutically induced by electroconvulsive therapy (ECT) (childhood febrile seizures are acceptable and these subjects may be included in the study), history of epilepsy in self or first degree relatives
* For subjects age \> 59 years, a total scaled score \< 8 on the Dementia Rating Scale-2.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
60 Years
Maximum Age:
80 Years
Study:
NCT03406195
Study Brief:
Protocol Section:
NCT03406195