Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 10:46 PM
Ignite Modification Date:
2025-12-26 @ 10:46 PM
NCT ID:
NCT04347512
Eligibility Criteria:
Inclusion Criteria:
* Age \> 18 years old
* Positive Sars-CoV-2 RT-PCR on nasopharyngeal swab
* CT scan suggestive of Sars-CoV-2 pneumonia
Exclusion Criteria:
* Negative Sars-CoV-2 RT-PCR on nasopharyngeal swab
* Known hypersensitivity to Hydroxychloroquine, Azithromycin or a macrolide family member
* Long term prescribed treatment contraindicated with azithromycin (colchicine, ergotamine, dihydroergotamine) and/or hydroxychloroquine (citalopram, escitalopram, hydroxyzine, domperidone, piperaquin)
* Retinopathy or maculopathy
* Porphyria
* Severe renal failure (GFR less than 30 mL/min/m²)
* Dyskaliemia, (ie less than 3,5 mmol/L or more than 5,5 mmol/L)
* Hypomagnesiemia, ie less than 0,7 mmol/L
* Severe cholestasis, cirrhosis or severe hepatic failure
* Known cardiac medical history of congestive heart failure or myocardial infarction
* Bradycardia less than 50 beats per minute
* Prolonged corrected QT interval, (ie cQT more than 440 ms in men and 450 ms in women) or medical history of ventricular cardiac rhythm disorders
* Blood disorders with history of hematopoietic stem cells allograft
* Known history of G6PD deficiency
* Pregnancy
* Breastfeeding
* Subject protected by law under guardianship of curatorship
* Inability to take oral medications
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04347512
Study Brief:
Protocol Section:
NCT04347512