Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 10:46 PM
Ignite Modification Date:
2025-12-26 @ 10:46 PM
NCT ID:
NCT00058812
Eligibility Criteria:
INCLUSION CRITERIA:
* All patients receiving a T cell depleted BMT from a mismatched family member or unrelated donor will be eligible for this protocol. In addition, patients receiving a matched sibling transplant or T replete transplant may be eligible if they are at high risk of developing EBV LPD because of their underlying disease (e.g Wiskott-Aldrich or Ataxia Telangiectasia) or have a past history of EBVLPD or other EBV associated malignancy.
* O2 saturation \> 90% on room air
EXCLUSION CRITERIA:
\- Exclusion criteria for BMT will be as detailed in the relevant protocol.
Exclusion criteria at time of administration CTLs:
* Patients with GVHD of Grade II or greater.
* Patients with severe renal disease (i.e., creatinine clearance less than half normal for age).
* Patients with severe hepatic disease (bilirubin greater than twice normal, or SGOT greater than 3 x normal).
* Patients with a severe intercurrent infection.
* Patients with a life expectancy \<6 weeks
Healthy Volunteers:
False
Sex:
ALL
Study:
NCT00058812
Study Brief:
Protocol Section:
NCT00058812