Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:44 PM
Ignite Modification Date:
2025-12-24 @ 11:44 PM
NCT ID:
NCT06216951
Eligibility Criteria:
Inclusion Criteria:
* Patients aged between 7 and 70 years
* The teeth with diagnosis of irreversible symptomatic pulpitis
* Permanent first and second molars with vital pulp
* PAI ≤ 2 with vital pulp. (Ørstavik D, Kerekes K, \& Eriksen HM (1986) The periapical index: A scoring system for radiographic assessment of apical periodontitis Dent Traumatol 2(1) 20-34, https://doi.org/10.1111/j.1600-9657.1986.tb00119.x.)
Exclusion Criteria:
* Clinical or radiographic signs of a necrotic pulp
* The presence of a sinus, buccal tenderness, pathological mobility or evidence of pathology on a periapical radiograph
* Teeth with horizontal or vertical root fractures
* Swelling, acute endodontic, or periodontal abscess
* Insufficient tooth tissue for a restoration, teeth requiring a post
* Unable to give informed consent
* Contraindicated systemic disease
* Allergies the local anesthesia
* Antibiotics, biphosphonates, and corticosteroid intake during the 7 days before treatment.
* Pregnancy or breastfeeding.
* Patients who needed endodontic treatment on several teeth to avoid a potentially confused pain referral.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
7 Years
Maximum Age:
70 Years
Study:
NCT06216951
Study Brief:
Protocol Section:
NCT06216951