Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 10:45 PM
Ignite Modification Date:
2025-12-26 @ 10:45 PM
NCT ID:
NCT07128212
Eligibility Criteria:
Inclusion Criteria:
* Age 45-60 years.
* Provides written informed consent.
* WMIL group: consecutive outpatients/inpatients from the Neurology Department of Suzhou Municipal Hospital, with WMIL confirmed by brain MRI. Diagnostic features: symmetric, diffusely distributed, ill-defined lesions in periventricular and subcortical white matter; iso- or hypointense on T1WI; hyperintense on T2WI and FLAIR.
* Control group: healthy individuals aged 45-60 years with brain MRI showing no intracranial lesions.
Exclusion Criteria:
* Acute intracerebral hemorrhage or acute infarction on brain MRI or CT.
* Central nervous system diseases that severely affect cognition, such as Alzheimer's disease or frontotemporal dementia.
* White matter lesions due to other causes (e.g., toxic, genetic, immune, infectious, neoplastic, radiation-related).
* Severe hepatic, renal, or cardiac insufficiency.
* Recent major surgery or severe trauma.
* History of psychiatric disorders that would preclude completion of study scales.
* Unable to provide written informed consent.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
45 Years
Maximum Age:
60 Years
Study:
NCT07128212
Study Brief:
Protocol Section:
NCT07128212