Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:44 PM
Ignite Modification Date:
2025-12-24 @ 11:44 PM
NCT ID:
NCT05365451
Eligibility Criteria:
Inclusion Criteria:
Are from 18-65 years old and healthy
* Are not taking any medications (prescription and non-prescription) or dietary/herbal supplements that can interfere with your ability to eliminate the study drugs from your body
* Are willing to stop taking dietary/herbal supplements and citrus juices for several weeks
* Are willing to stop consuming caffeinated beverages or other caffeine-containing products the evening before and the morning of the first day of each study arm
* Are willing to stop drinking alcoholic beverages for at least 1 day prior to any study day and during the study day
* Are willing to use an acceptable method of birth control that does not include oral contraceptive pills or patches (such as abstinence, copper IUD, condom) throughout your participation in the study and for at least 3 weeks after you last take the study drugs
* Have the time to participate
Exclusion Criteria:
* Are under 18 or over 65 years old
* Smoke/vape/chew tobacco products
* Use cannabis products, including marijuana, hemp, and other THC- and CBDcontaining products• Are taking medications or dietary/herbal supplements that can interfere with your ability to eliminate the study drugs from your body
* Have a chronic illness such as (but not limited to) kidney disease, liver disease, diabetes mellitus, high blood pressure, coronary artery disease, chronic obstructive pulmonary disease, cancer, or HIV/AIDS
* Have a hematologic (blood) disorder
* Have a history of drug or alcohol addiction or major psychiatric illness
* Have a history of allergy to metformin, cimetidine, furosemide, or probenecid
* Are pregnant, nursing, or plan to become pregnant within 3 weeks after participation
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT05365451
Study Brief:
Protocol Section:
NCT05365451