Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:43 PM
Ignite Modification Date:
2025-12-24 @ 11:43 PM
NCT ID:
NCT02413151
Eligibility Criteria:
Inclusion Criteria:
* Patients with chronic heart failure (CHF), classified in NYHA functional class III or IV;
* Receiving optimal medical therapy for CHF (including an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker and a beta-blocker unless a contraindication is evident) with a stable condition for more than 1 month (no hospitalization for HF, no change in medication, and no change in NYHA functional class);
* Left ventricular ejection fraction (LVEF) \< 35%;
* QRS duration ≥ 120 ms.
Exclusion Criteria:
* If they are younger than 18 years or are unable to sign informed consent;
* Patients who had been treated with an intravenous inotropic agent within the 30 days prior to implantation (these medications affect endothelial function after they are discontinued);
* Unstable angina pectoris;
* Orthopedic or neurological limitations to exercise.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02413151
Study Brief:
Protocol Section:
NCT02413151