Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:40 PM
Ignite Modification Date:
2025-12-24 @ 11:40 PM
NCT ID:
NCT01847651
Eligibility Criteria:
Inclusion Criteria:
* Ambulant patients of any Child-Pugh stage cirrhosi and PHEs defined MHe or grade 1 encephalopathy
Exclusion Criteria:
* Previous episodes of overt HE without a clear precipitant
* Recurrent excessive alcohol consumption (abstinence for those with alcoholic liver disease otherwise less than 28 units per week)
* Severe coagulopathy (INR\>2, platelets \<60 000/uL, Fibrinogen \<1mg/dl)
* known myopathy or myositis, taruma to lower extremities within 3 months)
* Renal dysfunction with a serum creatinine\>3mg/dl (265micromol/L)
* Ferromagnetic implants
* Recent intestinal haemorrhage within 1 month
* Claustrophobia
* Weight \>120kg
* Major psychoactive medication such as antipsychotic agents
* Known cerebrovascular disease or pre-existing neurological conditions
* Age less than 18 or greater than 65.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT01847651
Study Brief:
Protocol Section:
NCT01847651