Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:40 PM
Ignite Modification Date:
2025-12-24 @ 11:40 PM
NCT ID:
NCT05321251
Eligibility Criteria:
Inclusion Criteria:
* Diagnosis of neurotrophic keratitis with persistent epithelial defect that has been refractory to conventional treatments for at least 2 weeks
* 18 years or older
* Able to provide informed consent
* Failed other conventional treatments for neurotrophic keratitis
* Understanding and accepting of use of topical insulin alone
Exclusion Criteria:
* Less than 18 years old
* Pregnant or breastfeeding women
* Unable to provide informed consent
* Unable to comply with tests/follow-up
* Lid function abnormalities (e.g., lagophthalmos, entropion, ectropion, or abnormal orbicularis function from cranial nerve 7 palsy or Bell's palsy)
* Patients who require ongoing topical treatment (e.g. topical ganciclovir)
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT05321251
Study Brief:
Protocol Section:
NCT05321251