Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:39 PM
Ignite Modification Date:
2025-12-24 @ 11:39 PM
NCT ID:
NCT05813951
Eligibility Criteria:
Inclusion Criteria:
* adult patients aged \> 18 years old
* diagnosis of septic shock (patient with septic shock can be clinically identified by a vasopressor requirement to maintain a mean arterial blood pressure of 65 mm Hg or greater and serum lactate level greater than 2 mmol\\L (\>18 mg\\dL) in the absence of hypovolemia).
* positive culture confirming linezolid susceptibility.
Exclusion Criteria:
* Patient refusal.
* Known allergy to linezolid.
* Pregnancy and lactation.
* Severe hepatic failure (Child-Pugh C).
* Thrombocytopenia (platelet count \< 80,000/mm3).
* Disseminated intravascular coagulation (DIC).
* Hematologic disease, and concurrent use of other medications that may interact with linezolid (i.e., macrolides, serotonin modulators), or drug-associated thrombocytopenia.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT05813951
Study Brief:
Protocol Section:
NCT05813951